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OpenSPR Binding Data Uncovers Virulence Mechanism of Streptococcus pyogenes
Virulence factors are tools employed by pathogenic organisms to utilize, evade, colonize, suppress or destroy normal immune responses in a host. An example of a virulence factor is lipid A, a componen...
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Pros & Cons of Fluorescence-Based Binding Assays
As the availability of affordable technology increases, reviewers are constantly requesting binding data during the publishing process. However, measuring only affinity or obtaining simplistic yes/no ...
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How SPR Fits in Your Interaction Research Workflow
Trends in Publications How do you measure success as an academic researcher? Although there are many paths that a scientific research project takes, the end goal remains the same; publishing your work...
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Advancing Neuromuscular Disease Research with OpenSPR Binding Data
The human nervous system is a complex collection of over 100 billion nerve cells that regulate countless processes within the body. Within the processes of the muscular system, nerve and muscle cells ...
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OpenSPR Binding Data Advances Delivery Method of Photodynamic Cancer Therapeutics
Dr. Xiaofeng Liu recently published a paper using binding data generated from OpenSPR to reveal an effective affibody-based photosensitizer carrier used in Photodynamic Therapy (PDT), a less invasive ...
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OpenSPR-XT Binding Data Opens New Doors for Targeting of RNA Binding Proteins for Glioblastoma Therapeutics
Dr. Luis Penalva recently published a paper using binding data generated from the OpenSPR-XT’s automated SPR technology assessing the effectiveness of luteolin binding to RNA binding protein, Msi1. ...
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Discovery of a Gene Regulation Network in P. aeruginosa Biofilm Production using OpenSPR Binding Data
Dr. Tung T. Hoang recently published a paper using binding data generated from OpenSPR to quantify the formation of a stable complex between 2 co-regulators of biofilm production and their target DNA ...
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The OpenSPR Centre of Excellence – Building a Community of Innovative Researchers in India & Beyond
Dr. Ramaswamy (Dr. Rams) is a leading scientist in India with over 100 publications to date. In collaboration with Dr. Rams and his lab, Nicoya hosted the grand opening of the “OpenSPR Centre of Exc...
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OpenSPR Binding Data Advances Peptide Screening Methods
Dr. Leonard Luyt recently published a paper using binding data generated from the OpenSPR to quantify the binding behaviour of a chemically synthesized 7 kDa RHAMM “mini-protein” engineered for sc...
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OpenSPR Binding Data Advances Targeting Potential of Anti-Cancer Therapeutics
Dr. Huile Gao recently published a paper that unveils how protein corona formation may significantly reduce the interaction potential of ligand-modified PNs to target TfR, a common target for anti-can...
