Antibody Interactions

Quantitatively characterize your interaction with binding kinetics & affinity data. 

Antibody_Antigen

Antibody-Antigen

Ligand: Anti-PSA immobilized onto Gold Sensor with custom chemistry

Analyte: PSA

kon = 4.0×104 M-1s-1

koff = 1.8×10-6 s-1

KD = 4.5 nM

CV=3.2%

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Outcomes:

  • Determine kon and koff (kinetics) and KD (affinity) values
  • Quantify levels of protein at different development stages and expression levels
  • Yes/No binding
  • Determine presence of protein and antibody
  • Determine levels of crude antibody titer
  • Screening for ligand binding partners
  • Specificity

Use Cases:

  • Expressed protein interactions
  • Extracted protein interactions
  • Crude lysate binding detection and relative quantification
  • Antibodies
  • Quality control
  • Drug discovery

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OpenSPR-Instrument

Overview

OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.

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