• OpenSPR Binding Data Reveals a Potential Mechanism for the Treatment of Depression

  Introduction Depression is becoming more and more common worldwide, with approximately 1 in 30 people being affected by the illness1. Resulting from a combination of genetic, social and psychological ...

• Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling

  Adikaram, P. R., Zhang, J.-H., Kittock, C. M., Pandey, M., Hassan, S. A., Lue, N. G., … Simonds, W. F. (2019). Development of R7BP inhibitors through cross-linking coupled mass spectrometry and inte...

• A genetically encoded probe for imaging nascent and mature HA-tagged proteins in vivo

  Zhao, N., Kamijo, K., Fox, P. D., Oda, H., Morisaki, T., Sato, Y., Kimura, H., Stasevich, T. J. Nature Communications. (2019). Interaction Type: Protein-Protein Abstract: To expand the toolbox of imag...

• Phenothiazine antipsychotics exhibit dual properties in pseudo-allergic reactions: Activating MRGPRX2 and inhibiting the H1 receptor

  Hou, Y., Che, D., Wei, D., Wang, C., Xie, Y., Zhang, K., Cao, J., Fu, J., Zhou, N., He, H. Molecular Immunology. (2019). Interaction Type: Protein-Small Molecule Abstract: Phenothiazines are a class o...

• Influencing early stages of neuromuscular junction formation through glycocalyx engineering

  Godula, K., Huang, M. L., Lucas, T. M., and Tota, E. M. ACS Chemical Neuroscience. (2018). Interaction Type: Protein-Protein Read Publication...

• Sertraline ameliorates inflammation in CUMS mice and inhibits TNF-α-induced inflammation in microglia cells

  Lu, Y., Xu, X., Jiang, T., Jin, L.,  Zhao, X-D., Cheng, J-H., Jin, X-J., Ma, J., Piao, H-N., and Piao, L-X. International Immunopharmacology. (2019). Interaction Type: Protein-Small Molecule Read...

• The small RbcS-like domains of the b-carboxysome structural protein, CcmM, bind RubisCO at a site distinct from that binding the RbcS subunit

  Ryan, P., Forrester, T. J. B., Wroblewski, C., Kenney, T. M. G., Kitova, E. N., Klassen, J. S., and Kimber, M. S. JBC Papers in Press. (2018). Interaction Type: Protein-Protein Read Publication...

• Nanoparticles Targeted against Cryptococcal Pneumonia by Interactions between Chitosan and Its Peptide Ligand

  Tang, Y., Wu, S., Lin, J., Cheng, L., Zhou, J., Xie, J., Huang, K., Wang, X., Yu, Y., Chen, Z., et al. ACS Nano Letters. (2018). Interaction Type: Protein-Peptide Read Publication...

• Two Regulators, PA3898 and PA2100, Modulate the Pseudomonas aeruginosa Multidrug Resistance MexAB-OprM and EmrAB Efflux Pumps and Biofilm Formation

  Heacock-Kang, Y., Sun, Z., Zarzycki-Siek, J., Poonsuk, K., McMillan, I. A., Chuanchuen, R. and Hoang, T. T. ASM Antimicrobial Agents and Chemotherapy. (2018). Interaction Type: Protein-Nucleic Acid Re...

• Novel dual regulators of Pseudomonas aeruginosa essential for productive biofilms and virulence

  Heacock‐Kang, Y., Zarzycki‐Siek, J., Sun, Z., Poonsuk, K., Bluhm, A. P., Cabanas, D., Fogen, D., McMillan, I. A., Chuanchuen, R. and Hoang, T. T. Molecular Microbiology. (2018). Interaction Type: ...