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OpenSPR Binding Data Reveals a Potential Mechanism for the Treatment of Depression
Introduction Depression is becoming more and more common worldwide, with approximately 1 in 30 people being affected by the illness1. Resulting from a combination of genetic, social and psychological ...
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Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling
Adikaram, P. R., Zhang, J.-H., Kittock, C. M., Pandey, M., Hassan, S. A., Lue, N. G., … Simonds, W. F. (2019). Development of R7BP inhibitors through cross-linking coupled mass spectrometry and inte...
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A genetically encoded probe for imaging nascent and mature HA-tagged proteins in vivo
Zhao, N., Kamijo, K., Fox, P. D., Oda, H., Morisaki, T., Sato, Y., Kimura, H., Stasevich, T. J. Nature Communications. (2019). Interaction Type: Protein-Protein Abstract: To expand the toolbox of imag...
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Phenothiazine antipsychotics exhibit dual properties in pseudo-allergic reactions: Activating MRGPRX2 and inhibiting the H1 receptor
Hou, Y., Che, D., Wei, D., Wang, C., Xie, Y., Zhang, K., Cao, J., Fu, J., Zhou, N., He, H. Molecular Immunology. (2019). Interaction Type: Protein-Small Molecule Abstract: Phenothiazines are a class o...
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Influencing early stages of neuromuscular junction formation through glycocalyx engineering
Godula, K., Huang, M. L., Lucas, T. M., and Tota, E. M. ACS Chemical Neuroscience. (2018). Interaction Type: Protein-Protein Read Publication...
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Sertraline ameliorates inflammation in CUMS mice and inhibits TNF-α-induced inflammation in microglia cells
Lu, Y., Xu, X., Jiang, T., Jin, L., Zhao, X-D., Cheng, J-H., Jin, X-J., Ma, J., Piao, H-N., and Piao, L-X. International Immunopharmacology. (2019). Interaction Type: Protein-Small Molecule Read...
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The small RbcS-like domains of the b-carboxysome structural protein, CcmM, bind RubisCO at a site distinct from that binding the RbcS subunit
Ryan, P., Forrester, T. J. B., Wroblewski, C., Kenney, T. M. G., Kitova, E. N., Klassen, J. S., and Kimber, M. S. JBC Papers in Press. (2018). Interaction Type: Protein-Protein Read Publication...
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Nanoparticles Targeted against Cryptococcal Pneumonia by Interactions between Chitosan and Its Peptide Ligand
Tang, Y., Wu, S., Lin, J., Cheng, L., Zhou, J., Xie, J., Huang, K., Wang, X., Yu, Y., Chen, Z., et al. ACS Nano Letters. (2018). Interaction Type: Protein-Peptide Read Publication...
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Two Regulators, PA3898 and PA2100, Modulate the Pseudomonas aeruginosa Multidrug Resistance MexAB-OprM and EmrAB Efflux Pumps and Biofilm Formation
Heacock-Kang, Y., Sun, Z., Zarzycki-Siek, J., Poonsuk, K., McMillan, I. A., Chuanchuen, R. and Hoang, T. T. ASM Antimicrobial Agents and Chemotherapy. (2018). Interaction Type: Protein-Nucleic Acid Re...
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Novel dual regulators of Pseudomonas aeruginosa essential for productive biofilms and virulence
Heacock‐Kang, Y., Zarzycki‐Siek, J., Sun, Z., Poonsuk, K., Bluhm, A. P., Cabanas, D., Fogen, D., McMillan, I. A., Chuanchuen, R. and Hoang, T. T. Molecular Microbiology. (2018). Interaction Type: ...