• Characterization of Biomolecular Interactions using Alto™: Comparison to Conventional SPR

  Overview Label-free analysis of biomolecular interactions is a critical tool for the development of biologics. Conventional label free analytical instruments require relatively large amounts of sample...

• Kinetic and epitope characterization of influenza antiviral targets using Alto™ digital surface plasmon resonance

  Overview Rapid changes in influenza antiviral target proteins due to antigenic drift result in cloaking of the influenza virus from the immune system of vaccinated hosts. Hence, annual formulation upd...

• Binding of SARS-CoV-2 Antibody to the Spike Protein Receptor Binding Domain Using OpenSPR-XT™

  Overview The analysis of binding kinetics with SPR plays a critical role in the understanding of COVID-19. This includes basic research for understanding the viral infection mechanisms, the developmen...

• Binding Kinetics of a Virus-Like Particle using OpenSPR-XT™

  Overview Virus-like particles (VLPs) are complex molecules composed of multiple subunits that resemble a specific virus without its genetic material. VLPs are frequently used to study viruses without ...

• Protein A – IgG Interaction Analysis Using Alto™

  Alto™ is a high-throughput benchtop surface plasmon resonance (SPR) instrument providing detailed binding kinetics and affinity data for a wide variety of molecular interactions. Alto™ uses digita...

• Binding Kinetics of an Antibody Serum Sample Using OpenSPR™

  A common application of the SPR technique is antibody screening, which is critical to the development of vaccines and other immunotherapies. Since this development often involves screening animal sera...

• Comparison Study of Label-Free Biosensors Using Commercially Relevant Binding Systems

  Overview The OpenSPR™ is a powerful instrument providing researchers with in-depth label-free binding kinetics for a variety of different molecular interactions. A side by side comparison study was ...

• Binding Kinetics of Aptamer-Protein Interactions using OpenSPR

  Overview OpenSPR™ is a powerful instrument providing in-depth label-free binding kinetics for a variety of different molecular interactions. One of the most common applications of surface plasmon re...

• Binding Kinetics of Glycoprotein Interactions using OpenSPR

  Overview OpenSPR™ is a powerful instrument providing in-depth label-free binding kinetics for a variety of different molecular interactions. One of the most common applications of surface plasmon re...

• Binding Kinetics of Protein-Protein Interactions using OpenSPR

  Overview OpenSPR™ is a powerful instrument providing in-depth label-free binding kinetics for a variety of different molecular interactions. One of the most common applications of surface plasmon re...