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Preparing for Publication: Identification and Characterization
In our previous blog post, we explored some of the most commonly used structures for expression and purification of your protein binding partners. The expression systems we addressed included bacteria...
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Preparing for Characterization: Expression and Purification
When proposing a research project, there’s a number of project steps that require advanced planning. Asking questions like, “do I need to express and purify any protein(s)?”, and accounting for ...
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Comparison Study of Label-Free Biosensors Using Commercially Relevant Binding Systems
Summary Binding kinetics of biotinylated CD16a and IgG were characterized by comparing OpenSPR™ with a standard SPR instrument and a commonly-used BLI instrument. KD values measured using the OpenSP...
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Our Mission: Improving Human Life by Helping Scientists Succeed
How is your research changing the world? Over the past 5 years, we’ve had the opportunity to help over 500 researchers worldwide succeed in their area of study. As we worked alongside these innovati...
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OpenSPR Binding Data Uncovers Virulence Mechanism of Streptococcus pyogenes
Virulence factors are tools employed by pathogenic organisms to utilize, evade, colonize, suppress or destroy normal immune responses in a host. An example of a virulence factor is lipid A, a componen...
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Pros & Cons of Fluorescence-Based Binding Assays
As the availability of affordable technology increases, reviewers are constantly requesting binding data during the publishing process. However, measuring only affinity or obtaining simplistic yes/no ...
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How SPR Fits in Your Interaction Research Workflow
Trends in Publications How do you measure success as an academic researcher? Although there are many paths that a scientific research project takes, the end goal remains the same; publishing your work...
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Advancing Neuromuscular Disease Research with OpenSPR Binding Data
The human nervous system is a complex collection of over 100 billion nerve cells that regulate countless processes within the body. Within the processes of the muscular system, nerve and muscle cells ...
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OpenSPR Binding Data Advances Delivery Method of Photodynamic Cancer Therapeutics
Dr. Xiaofeng Liu recently published a paper using binding data generated from OpenSPR to reveal an effective affibody-based photosensitizer carrier used in Photodynamic Therapy (PDT), a less invasive ...
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OpenSPR-XT Binding Data Opens New Doors for Targeting of RNA Binding Proteins for Glioblastoma Therapeutics
Dr. Luis Penalva recently published a paper using binding data generated from the OpenSPR-XT’s automated SPR technology assessing the effectiveness of luteolin binding to RNA binding protein, Msi1. ...