-
Biolayer Interferometry vs Surface Plasmon Resonance Comparison
Deciding which methods your lab should invest in can be challenging. Cost, experiment time and reproducibility are likely the three most important factors during your evaluation process. We understand...
-
New Publication – OpenSPR Binding Data Enhances Nanotherapeutic Construction with Molecular Affinity Strategy
In order for drugs to fight diseases, an efficient delivery method must be found. This necessitates an important area of study to ensure that drugs can effectively combat diseases. A subsection of thi...
-
How to Confront the Antibody Reproducibility Crisis using SPR
Have you ever ordered antibodies from an antibody supplier? Have you ever had a problem with antibody specificity, selectivity and reproducibility? Have you ever returned your antibodies back to the s...
-
The ABC’s of Competitive Binding Assays with SPR
In the arena of drug discovery, there are a number of tools available for researcher’s to characterize binding behaviours of low molecular weight compounds with their target(s). These tools may incl...
-
OpenSPR Binding Data Uncovers Antipsychotic Drug Mechanisms
Over the last number of years, there’s been an increasing amount of attention on combating mental illness and the associated stigma. Notably, psychiatric counseling is an important facet of treatmen...
-
Technical Guide: Binding Assays with Flow Cytometry and SPR
Flow cytometers are excellent tools for the modern cell biologist and immunologist. They can provide a wide range of information which help researchers discern various cellular physical and chemical c...
-
Preparing for Publication: Identification and Characterization
In our previous blog post, we explored some of the most commonly used structures for expression and purification of your protein binding partners. The expression systems we addressed included bacteria...
-
Preparing for Characterization: Expression and Purification
When proposing a research project, there’s a number of project steps that require advanced planning. Asking questions like, “do I need to express and purify any protein(s)?”, and accounting for ...
-
Comparison Study of Label-Free Biosensors Using Commercially Relevant Binding Systems
Summary Binding kinetics of biotinylated CD16a and IgG were characterized by comparing OpenSPR™ with a standard SPR instrument and a commonly-used BLI instrument. KD values measured using the OpenSP...
-
Our Mission: Improving Human Life by Helping Scientists Succeed
How is your research changing the world? Over the past 5 years, we’ve had the opportunity to help over 500 researchers worldwide succeed in their area of study. As we worked alongside these innovati...
