Blog
Educational material, comparison studies and publications on SPR and other related techniques for researchers.
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OpenSPR Binding Data Helps Advance Ageing & Cancer Research
Dr. Roth, a researcher at the Medical University of South Carolina, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-protein interaction, helping them discover a direct link between telomere damage–dependent senescence and apoptosis with regards to aging and cancer.
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SPR, ITC, MST & BLI: What’s the optimal interaction technique for your research?
Currently, the four most used techniques are Surface Plasmon Resonance (SPR), Isothermal Titration Calorimetry (ITC), Microscale Thermophoresis (MST), and Biolayer Interferometry (BLI). Each technique has its advantages and disadvantages. Read our SPR, ITC, MST & BLI comparison and take a 5 minute quiz to determine the optimal technique for your research.
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How Dr. Piazza uses SPR to complement NMR data for protein structure-function publications
Dr. Piazza, PhD graduate from the University of Waterloo, uses both NMR & OpenSPR’s surface plasmon resonance technology to get the key binding data needed for his recent publication on protein-peptide interaction.
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8 Ways to Make The Most Of Your Leftover Research Funding
As the fiscal year end quickly approaches, we understand how hard it is to juggle purchasing lab equipment and chemical reagents, while trying to meet publication deadlines. Read “8 Ways to Make the Most of Your Leftover Funding” to see how you can spend your leftover funding to accelerate your research with OpenSPR & publish within 3 months.
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OpenSPR Binding Data Helps Advance Cancer Drug Discovery
Dr. Lu, a researcher at Sichuan University, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-protein interaction, helping them discover a new strategy for tumor-targeted delivery of anticancer agents.
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SPR Binding Data Advances Muscular Dystrophy Research
Are you missing quantitative binding data data in your publication? Dr. Rossi, a collaborative researcher at the University of Virginia, uses OpenSPR’s surface plasmon resonance technology to provide her with the key binding data needed for her recent publication on protein-protein interaction in muscular dystrophy.
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SPR Expert Interview: Dr. George Espie
Meet SPR Expert: Dr. George Espie. Dr. Espie is a Professor of Biology at the University of Toronto Mississauga & Graduate Program Cell & Systems Biology at the University of Toronto. When he isn’t lecturing, you can find him in his lab working on innovative protein-protein research. With over 23 publications we interviewed Dr. Espie […]
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Waterloo Professor Thorsten Dieckmann Says SPR Data Was Key Link Needed For Publication
Dr. Dieckmann, Mike Piazza and Dr. Guillemette from the University of Waterloo published a paper that uses OpenSPR to study the structure and function of the protein calmodulin (CaM). CaM is a small protein important for many physiological and pathological processes, and serves as a calcium sensor and control element for nitric oxide synthases (NOS). […]
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How OpenSPR helped Dr. Espie Publish his Groundbreaking Research
Do you want to publish your research sooner? Dr. George Espie from the University of Toronto reveals how OpenSPR helped him accelerate his research and publish within 3 months.The research paper “The structure, kinetics and interactions of the β-carboxysomal β-carbonic anhydrase, CcaA” published in Biochemical Journal uses surface plasmon resonance data generated with OpenSPR to study the […]
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Comparison Study of SPR Instruments Using Commercially Relevant Binding Systems
Comparison Study of SPR Instruments Using Commercially Relevant Binding Systems: A protein-protein interaction was analyzed on the OpenSPR™ and the standard SPR insturment. Kinetic analysis was used to determine the on rate, off rate, and affinity constant of the protein-protein interaction. Both data sets generated from OpenSPR™ and the comparison SPR instrument show excellent fits […]