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New Nature study reveals insights into de novo autoreactivity in severe COVID-19 using Altoâ„¢ Digital SPR
Kinetic analysis of de novo autoreactivity in severe COVID-19 reveals important implications for early intervention and treatment in patients with post-COVID sequelae. The SARS-CoV-2 outbreak was firs...
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Targeting interleukins: How digital SPR accelerates monoclonal antibodies for immune-related diseases
Alto’s unmatched ability to seamlessly characterize mAbs make it the optimal fit for biologics developers. Read our latest application note on digital SPR analysis of the interleukin-6 receptor (IL-...
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Cancer detection using SPR: Announcing our partnership with INOVIQ
The SubB2M™-based SPR test will detect for pan-cancer biomarker Neu5Gc in blood samples on Alto™, and will initially be used as a cancer risk assessment test. We’re excited to announce our partn...
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Application note: Characterization of ImmTAC® bispecific molecules with Alto™ digital SPR
Immunocore’s ImmTAC technology is a novel class of biologics that target cancer cells through T-cell redirecting immunotherapy. Bispecific molecules, or bispecifics, are a growing subset of biothera...
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Conventional vs Digital SPR: Comparing label-free tools for biologics discovery and development
In this blog, we break down the difference between conventional and digital surface plasmon resonance (SPR) systems to help you select the right solution for your lab. Introduction Biomolecular ...
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What’s in store for 2022? Announcing our $20M Series A Extension
Equipping biologics researchers with disruptive tools in the era of proteomics Ryan Denomme, Co-founder and CEO At Nicoya, we build proteomics tools to provide researchers with powerful insights while...
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The role of SPR in immunotherapeutic research
Read on to learn about the insights that Surface Plasmon Resonance (SPR) can provide for immunotherapeutic research. Introduction According to John Hopkins Medicine, almost 40 percent of the populatio...
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Analyzing binding kinetics: Which method is best for your next SPR experiment?
Read on to learn about the two most common approaches for measuring binding kinetics, multi-cycle kinetics (MCK) and single-cycle kinetics (SCK), and how to select the right one for your interaction....
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Nicoya receives over $1.9M in funding to continue the development of a portable, saliva-based COVID-19 test
The arrival of COVID-19 vaccines has tipped the scale in favor of winning the battle against the pandemic, but the war is far from over. Diagnostic tests, along with vaccines, are required to stop out...
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Cryo-EM and SPR: Complementary technologies providing structural and functional insights toward advancing coronavirus research
How did two cutting-edge technologies ultimately enable researchers to develop COVID-19 vaccines at an unprecedented rate? The development of COVID-19 vaccines is a seminal discovery of this dec...