Overview
Oligonucleotides hold great potential for treating diseases linked to gene expression and have recently revolutionized the vaccine industry with the remarkable success of mRNA-based COVID-19 vaccines. In this application note, we demonstrate the applicability of Alto™, Nicoya’s Digital surface plasmon resonance™ (SPR) instrument, to the development of oligonucleotide systems in various
therapeutic capacities. Alto is used to accurately and precisely measure affinities and provide on/off-rates equivalent to those obtained with conventional SPR.
