Binding Kinetics of Protein-Small Molecule Interactions using OpenSPR


OpenSPR™ is a powerful instrument providing in-depth label-free binding kinetics for a variety of different molecular interactions. One of the most common applications of surface plasmon resonance is the analysis and quantification of the interactions between proteins and small molecules. This is of significant importance in the pharmaceutical industry to help researchers identify and characterize new drugs. In this application note, OpenSPR™ is used to analyze the KD of the arginine kinase enzyme
with ATP and Creatine.