Blog
Educational material, comparison studies and publications on SPR and other related techniques for researchers.
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Improve Your SPR Data Quality by 4X with New High Sensitivity Sensors
Combined with 2-Channel benchtop SPR technology, High Sensitivity Sensors enable a 4x sensitivity increase with higher ligand immobilization levels while maintaining the same ligand concentration per injection.
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Binding Kinetics of Protein A and IgG using 2-Channel Benchtop SPR
The 2-Channel OpenSPR is ideal for generating high quality and highly reproducible binding data with less time and effort.
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OpenSPR Antibody Binding Data Challenges Traditional Hepatitis B Vaccination Strategies
Dr. Yu-Ching Lee recently published a paper challenging traditional hepatitis B vaccination (HBV) strategies through his study of antibody-antigen interactions.
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Nicoya redefines SPR with new affordable, benchtop 2-channel system
Nicoya releases their new 2-channel OpenSPR instrument. With the addition of a second channel and a number of automated and user-friendly features, the company is continuing their mission to help scientists solve their toughest research challenges in both industry and academia.
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OpenSPR Phospholipid Binding Data Advances Cardiac Health Research
Dr. Zeczycki, a researcher at East Carolina University, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-lipid interaction. Results show that elevated levels of DHA may contribute to various metabolic disease via a reduction in cardiac mitochondrial enzyme activity.
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OpenSPR Binding Data Helps Advance Cervical Cancer Therapies
Dr. Zhang recently published a paper demonstrating the disruption potential of small molecules synthesized from taspine-derivatives to combat the Janus kinase/signal transducers and activators of transcription (JAK/Stat) signaling pathway, a known pathway in the development of cervical cancer. Read the full article to see how OpenSPR provided Dr. Zhang with the data needed to publish her protein-small molecule research.
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Determination of Protein Concentrations using OpenSPR
Looking for quick, easy and affordable protein concentration analysis? Benchtop SPR can help. In our application note, we demonstrate how OpenSPR™ can be used as a concentration assay for determining the level of α-lactalbumin, an important protein in milk.
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OpenSPR Binding Data Helps Advance Biotherapeutic Drug Discovery
Dr. Brown, a researcher at Lehigh University, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-peptide interaction, demonstrating the possibility of using target-based peptides to inhibit leukotoxin mediated cytotoxicity in human white blood cells.
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OpenSPR Binding Data Helps Advance Ageing & Cancer Research
Dr. Roth, a researcher at the Medical University of South Carolina, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-protein interaction, helping them discover a direct link between telomere damage–dependent senescence and apoptosis with regards to aging and cancer.
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SPR, ITC, MST & BLI: What’s the optimal interaction technique for your research?
Currently, the four most used techniques are Surface Plasmon Resonance (SPR), Isothermal Titration Calorimetry (ITC), Microscale Thermophoresis (MST), and Biolayer Interferometry (BLI). Each technique has its advantages and disadvantages. Read our SPR, ITC, MST & BLI comparison and take a 5 minute quiz to determine the optimal technique for your research.