Obtain publication-quality binding kinetics & affinity data on your benchtop.


Meet OpenSPR

  • Benchtop
  • User-Friendly
  • Real-Time Data
  • Low-Maintenance


OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.


Compatible Molecules:

  • Proteins
  • Peptides
  • Antibodies
  • Antibody variants
  • Nucleic acids
  • Lipids
  • Adeno-associated viruses (AAV)
  • Virus-like particles (VLPs)
  • Hormones/cytokines
  • Small molecules (application dependent)

Supported Assays:

  • Kinetics/affinity characterization
  • Concentration analysis
  • Yes/No binding
  • Competition assays
  • Epitope mapping

Technical Specifications

Association Rate (kon) 1×103–1×107 1/M*s
Dissociation Rate (koff) 0.1–1×10⁻⁵ 1/s
Affinity Range (KD) mM-pM
Number of Channels 2
Flow Rate 5–200 μL/min
Injection Semi-Automated
Injection Volume “50, 100, 250 or 500 μL (100 μL standard)”
Sample Volume 200 μL
Sample Capacity Injection volume + 50 μL
Autosampler Optional upgrade to OpenSPR-XT
Temperature Range 4°C – 40°C (lower limit 10°C below ambient temperature)
Temperature Precision +/- 0.25°C
Buffer Switching “3 ports available, automated switching”
Instrument Size 46 x 34 x 21 cm
Weight 17 kg
File Output “CSV, TXT compatible with TraceDrawer.”

OpenSPR for Biotechnology

Get started on your experiments in a matter of hours.

OpenSPR is user-friendly and has versatile applicability. In smaller companies, the OpenSPR allows researchers to finish off their full experimental workflows at a low cost. In larger companies, the OpenSPR is easily integrated alongside their other assays.

OpenSPR is ideal for:

  • Lead Optimization

  • Quality control

  • Drug discovery

  • Validation

  • Feasibility

OpenSPR for Academia

Our mission is to improve human life by helping scientists succeed.

By using innovative nanotechnology, we reduce the cost and complexity of SPR instrumentation and make it accessible to every researcher. Having OpenSPR in your own lab will eliminate the expensive costs and inconvenient travelling associated with using a shared instrument in a core facility.

OpenSPR is helping over 600 researchers publish in high-impact journals worldwide. 

Read our full list of publications.

Product Selection Guide (2)

Product Selection Guide

Accelerate your next discovery with our benchtop SPR solutions. Read our guide to learn which system is right for your lab.


Make your next scientific breakthrough with OpenSPR.