Run SPR analysis 24/7 with the world’s first fully automatable SPR system
Automating biologics discovery workflows is essential for addressing the growing demand to accelerate timelines and reduce costs in bringing innovative therapies to patients. While many analytical techniques have been integrated into automated workcells, SPR has lagged behind.
Nicoya’s Alto Digital SPR platform offers an easy-to-use, high-throughput platform that provides high-quality binding kinetics measurements. And now, the Alto Automation Suite™ is changing the status quo as the only fully automatable SPR platform.
The Alto Automation Suite simplifies automation with its intuitive API, pre-configured labware definitions and protocols, unique well-plate-based cartridges, and cloud-native software. Designed to eliminate common automation challenges, it empowers scientists to perform 24/7 unattended SPR analysis with ease.
Alto’s API is designed to make the creation of automation protocols easy and accessible. The API interface follows SiLA 2 automation standards and communication protocols, allowing for rapid integration of Alto with automation hardware, LIMS, scheduling, and data management software.
Nicoya offers support for automation integration for any customers needing help developing automated Alto protocols, or requiring a function or format not yet in the API library. Contact automation@nicoyalife.com to inquire about automation support services.
Alto is the only SPR system whose consumables are entirely contained within a robot-compatible, disposable cartridge. The cartridge contains 16 sensors and 88 wells, which can be mapped to those of a well-plate for easy labware definition for any automation platform and existing workflows. The pitch of the wells is compatible with single or 8-channel pipettes.
Alto is the only SPR system whose consumables are entirely contained within a robot-compatible, disposable cartridge. The cartridge contains 16 sensors and 88 wells, which can be mapped to those of a well-plate for easy labware definition for any automation platform and existing workflows. The pitch of the wells is compatible with single or 8-channel pipettes.
Alto and its cartridges are compatible with standard liquid handling platforms, plate hotels and robot arms. When operating as a full workcell, Alto can run fully unattended, with no need for buffer refills, sensor changes or any manual intervention, enabling screening of thousands of samples per week.
The Opentrons Flex® liquid handling platform is available for purchase together with the Alto. Specific labware definitions have been developed in collaboration with Opentrons, enabling a seamless integration between the two. Additionally, the Brooks Automation PreciseFlex™ Robot arm has also been rigorously tested for operation with the Alto Automation Suite and is recommended to be used for cartridge handling in the workcell.
