OpenSPR™ vs. Biacore™ vs. Octet™ Comparison Study


OpenSPR™ is a powerful instrument providing in-depth label-free binding kinetics for a variety of different molecular interactions. To demonstrate the powerful capabilities and accuracy of the OpenSPR™, a side by side comparison study was conducted against a Biacore™ 3000 and Octet™ RED96. The Biacore™and Octet™ systems, are commonly used for analyzing binding kinetics but cost hundreds of thousands of dollars, making them inaccessible to many researchers who need this data. To show that OpenSPR™ is able to generate comparable results to the Biacore™ and Octet™ for a fraction of the cost, an Fc-FcR interaction was analyzed using these three instruments under similar conditions.