Antibody Interactions
Quantitatively characterize your interaction with binding kinetics & affinity data.
Antibody-Antigen
Ligand: Anti-PSA immobilized onto Gold Sensor with custom chemistry
Analyte: PSA
kon = 4.0×104 M-1s-1
koff = 1.8×10-6 s-1
KD = 4.5 nM
CV=3.2%
Outcomes:
- Determine kon and koff (kinetics) and KD (affinity) values
- Quantify levels of protein at different development stages and expression levels
- Yes/No binding
- Determine presence of protein and antibody
- Determine levels of crude antibody titer
- Screening for ligand binding partners
- Specificity
Use Cases:
- Expressed protein interactions
- Extracted protein interactions
- Crude lysate binding detection and relative quantification
- Antibodies
- Quality control
- Drug discovery
See OpenSPR in Action
Discuss your workflows with an application scientist & see how benchtop SPR can help.
Overview
OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.
Make your next scientific breakthrough with OpenSPR.
Discuss your research applications with an SPR application scientist: