OpenSPR
Delivering publication-quality binding kinetics and affinity data to every lab bench for only $25K*.
BOOK A DEMOGet the data you've been missing with uncompromised SPR
Surface plasmon resonance (SPR) is essential in biologics research for binding kinetics, analyte concentration, and epitope mapping. However, high costs and technical complexity often limit access, requiring many labs to rely on outdated methods, shared facilities, or outsourced analysis.
The OpenSPR® platform was designed specifically to reduce the
cost and complexity of SPR assays to allow more labs access to the benefits of label-free SPR analysis. Utilizing our proprietary localized SPR (LSPR) technology, the OpenSPR platform provides accurate and robust data, but at a fraction of the cost of existing platforms.
|
Mechanism of signaling, action analyses |
|
|
Hybridoma, phage display screening |
|
|
Antibody-antigen, antibody-FC receptor kinetics |
|
|
Antibody titer |
|
|
Antigen characterization |
|
|
Antibody immune response in serum |
|
|
Virus particle characterization |
|
|
Reagent characterization (quality assessment) |
|
|
Proteins |
|
|
Peptides |
|
|
Antibodies |
|
|
Antibody variants |
|
|
Nucleic acids |
|
|
Lipids |
|
|
Adeno-associated viruses (AAV) |
|
|
Virus-like particles (VLPs) |
|
|
Hormones/cytokines |
|
|
Small molecules (application dependent) |
|
|
Fluidic Channels |
2 |
|
Flow Rate |
5 – 200 μL/min |
|
Sample Capacity |
1 (manual injection) |
|
Injection |
Semi-Automated |
|
Injection Volume |
50, 100, 250, or 500 μL
(100 μL standard) |
|
Sample Volume |
Injection volume + 50 μL |
|
# of Running Buffers |
3, automated switching |
|
Analysis Temperature and Precision |
4°C – 40°C (lower limit 10°C below ambient temperature) +/- 0.25°C |
|
File Output |
CSV, TXT compatible with TraceDrawer |
|
Association Range |
103 – 107 1/M*s |
|
Dissociation Range |
10-5 – 0.1 1/s |
|
Affinity Range |
pM – mM |
|
Molecular Detection Limit |
Application dependent |
|
Data Collection Rate |
10 Hz |
|
Power Requirement |
100 – 240 V, 50/60 Hz |
|
Dimensions (W x D x H) |
46 x 34 x 21 cm |
|
Weight |
17 kg |
Bringing SPR to your benchtop for under $30K*
LSPR operates similarly to traditional SPR, using light to measure biomolecular interactions in real time. The key difference is that LSPR detects absorbance wavelength shifts from metal nanoparticles, while SPR measures angle changes from a gold film. Both methods yield comparable kinetics and affinity data, but their optical properties have distinct implications.
By design, our LSPR systems are:
- Smaller and more affordable, with lower costs for instrument, consumables and service
- Less sensitive to environmental variations like temperature and vibration
- More cost-effective to operate with nanotechnology-based sensors
- Easier to use and maintain with less optical hardware complexity inside
OpenSPR offers benchtop SPR at a fraction of the cost of competitors WITHOUT compromising data quality.
OpenSPR Resources
App Notes
Learn more about how OpenSPR has been used across the industry to advance research.
pUBLICATIONS
OpenSPR affinity and kinetics data have been well-vetted and published by researchers worldwide.
WEBINARS
View this webinar to hear how OpenSPR is used to optimize nucleic acid and antibody binding assays.
*USD, applicable to customers in North America only, conditions may apply