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Quantifying monoclonal antibodies in serum with Altoâ„¢ Digital SPR
Overview As the first digital microfluidic (DMF) powered surface plasmon resonance (SPR) instrument ...
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Regeneration of His-tagged Streptavidin on OpenSPR® NTA Sensors Sensors
Overview Capture coupling techniques are advantageous to investigate biomolecular interactions as th...
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Characterization of HuCAL Fab-MH binding kinetics on Alto™ digital surface plasmon resonance using a Twin-Strep-tag® capture system
Overview In this application note, Altoâ„¢ digital SPR was used to characterize HuCAL Fab-MH kinetic...
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Accelerating influenza antibody therapeutics with Altoâ„¢ digital microfluidic-powered epitope binning and kinetics analysis
Overview Annual formulation updates for influenza vaccines and related antibody therapies are requir...
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Label-free characterization of transmembrane proteins using Altoâ„¢ digital SPR
Overview Many human diseases are known to be associated with transmembrane proteins (TPs), making th...
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Characterization of Altoâ„¢ Sample Preparation Precision and Accuracy Enabled by DMF
Overview Precise and accurate liquid handling is crucial to obtaining repeatable, high-quality data ...
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Epitope Characterization of Influenza Antiviral Targets Using Altoâ„¢
Overview Rapid changes in influenza antiviral target proteins due to antigenic drift result in cloak...
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Poster: Characterization of Therapeutic Antibodies using Digital SPR
Overview Alto is the world’s first SPR instrument to integrate digital microfluidics (DMF) with na...
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Screening of Unknown Antibodies in Complex Media with Altoâ„¢ Digital SPR
Overview Screening is a common tool used to quickly test activity of a large number of chemical or b...
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Characterization of biosimilars derived from PlantForm’s vivoXPRESS® technology with Alto™ Digital SPR
Overview Biological drugs, or biologics, have transformed patient outcomes worldwide due to their ab...
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Binding Kinetics of Complementary Oligonucleotide Sequences using OpenSPRâ„¢
Overview Oligonucleotides are an important area of biotechnological and pharmaceutical research, as ...
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Epitope Characterization of Influenza Targets using OpenSPRâ„¢
Overview Rapid changes in influenza antiviral target proteins due to antigenic drift result in cloak...
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Characterization of Fc Gamma Receptors and IgG Interactions using Altoâ„¢: Comparison to BLI
Overview Label-free analysis of biomolecular interactions is critical in the development of biologic...
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Label-Free Characterization of the Interleukin-6 Receptor and Anti-IL-6R Antibody Drug Tocilizumab using Altoâ„¢
Overview Therapeutic monoclonal antibodies are one of the fastest growing classes of drugs, and inte...
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Label-Free Characterization of ImmTAC® Bispecific Molecules for T-Cell Redirecting Immunotherapy using Alto™
Overview Bispecific proteins offer a promising new modality for the treatment of cancer and have sub...
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Kinetic and Epitope Characterization of Influenza Antiviral Targets Using Altoâ„¢ Digital Surface Plasmon Resonance
Overview Rapid changes in influenza antiviral target proteins due to antigenic drift result in cloak...
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Binding Kinetics of a Virus-Like Particle using OpenSPR-XTâ„¢
Overview Virus-like particles (VLPs) are complex molecules composed of multiple subunits that resemb...
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Binding Kinetics of Protein-Protein Interactions using OpenSPR
Overview OpenSPRâ„¢ is a powerful instrument providing in-depth label-free binding kinetics for a va...
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Temperature Dependent Binding Kinetics of Protein-Protein Interactions Using OpenSPR
Overview OpenSPRâ„¢ is a powerful instrument providing indepth label-free binding kinetics for a var...