Webinar On Demand

Label-free characterization of challenging transmembrane proteins using Alto digital SPR

Transmembrane proteins (TPs) serve as crucial conduits between the internal and external environments of cells, regulating ion and molecule passage and orchestrating cellular responses to external cues. They play pivotal roles in cellular signaling, cell-cell interactions, and various physiological processes, making them promising targets for novel therapeutics, including cell and gene therapies. Leveraging the unique properties of TPs, researchers can design targeted therapeutic strategies with improved efficacy, specificity, and safety profiles. However, isolating biologically relevant forms of TPs, particularly multi-pass TPs, presents formidable challenges due to their intricate structures and limited expression levels. Addressing this demand, ACROBiosystems has pioneered cutting-edge technology platforms tailored to the complexities of multi-pass TPs. This innovation has yielded a comprehensive suite of full-length, stabilized multi-pass TPs, including key therapeutic targets such as CD20, Claudin18.2, CD133, and others. Engineered to maintain native folding and high activity, these proteins serve as invaluable tools for advancing drug development and uncovering novel mechanisms of action. In collaboration with Nicoya, a cutting-edge technology company dedicated to supporting drug development through advanced analytical solutions, Nicoya’s Alto™ digital surface plasmon resonance (SPR) system was utilized to characterize the binding kinetics of several transmembrane proteins in detergent, nanodisc, and virus-like particle (VLP) formats. This webinar will showcase how the Alto digital SPR system provides high-quality data on challenging membrane protein candidates while significantly reducing sample consumption and time to results. Through this collaboration, researchers and pharmaceutical developers gain access to advanced technologies that enable the production, stabilization and precise characterization of challenging transmembrane protein interactions, accelerating the development of novel therapeutics and unlocking new frontiers in therapeutic targeting.

What You Will Learn:

Discover Nicoya’s cutting-edge digital SPR platform Alto™, which is revolutionizing the analytical development of biologically relevant multi-pass transmembrane proteins and overcoming industry challenges.
Learn about ACROBiosystems’ dynamic suite of stabilized multi-pass TPs, featuring key therapeutic targets like CD20, Claudin18.2, CD133, and more.
Gain insights into the potential of leveraging Alto digital SPR and ACROBiosystems transmembrane proteins for developing novel therapeutics for cellular and genetic disorders.

Please complete the form below.

"*" indicates required fields

First Name*

Last Name*

Email*

Job Title

Company

Country

Yes! Send me genuinely useful emails from Nicoya Life Science Inc. every now and then to help me stay up to date with SPR-related topics and Nicoya’s latest news. See our privacy policy, or contact us. You can unsubscribe at any time.

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Comments

This field is for validation purposes and should be left unchanged.

B-29 King Street East
Kitchener, ON, Canada
N2G 2K4

1.877.673.6777

Trusted by over 500 research labs worldwide.

Products

Applications

Resources

About

Labroots DART webinar popup

Introduction to Digital SPR and its use in assessing the
binding kinetics of DART (Drugs Acutely Restricted by Tethering)

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

This field is for validation purposes and should be left unchanged.

OpenSPR and Alto webinar popup

Streamlining characterization of biomolecular binding
kinetics with Alto™ and OpenSPR®

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Comments

This field is for validation purposes and should be left unchanged.

Rising Investigators Webinar Popup

Rising Investigators in SPR

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Phone

This field is for validation purposes and should be left unchanged.

Detecting Emerging Viral Variants

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Phone

This field is for validation purposes and should be left unchanged.

OCMS Webinar Popup

Detecting Emerging Viral Variants

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

This field is for validation purposes and should be left unchanged.

Laboratory Automation Webinar Popup

Laboratory Automation

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Name

This field is for validation purposes and should be left unchanged.

Navigating the Post-Covid Research Landscape Popup

Navigating the Post-Covid Research Landscape

"*" indicates required fields

First Name*

Last Name*

Busines Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Comments

This field is for validation purposes and should be left unchanged.

Covid-19 Diagnostics Using SPR Popup

Covid-19 Diagnostics Using SPR

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

This field is for validation purposes and should be left unchanged.

Binding Techniques Webinar Popup

Binding Techniques

"*" indicates required fields

First Name*

Last Name*

Job Title*

Company/Organization Name*

Business Email*

Phone

Country*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Name

This field is for validation purposes and should be left unchanged.

Enter the Nicosystem Webinar Popup

Enter the Nicosystem

"*" indicates required fields

First Name*

Last Name*

Business Email*

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

This field is hidden when viewing the form

webinar-name

Phone

This field is for validation purposes and should be left unchanged.

Publish Faster With Binding Kinetics & Affinity Data

Over 600 researchers worldwide are using OpenSPR™ to get the data reviewers are looking for. Read our brochure to learn more!

"*" indicates required fields

First Name*

Last Name*

Business Email*

Phone Number

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

Name

This field is for validation purposes and should be left unchanged.

Download Alto Brochure

The future of drug discovery is Alto.

Interested in learning more about how Alto can accelerate your drug discovery? Fill out the form below to download a product brochure.

"*" indicates required fields

First Name*

Last Name*

Business Email*

Phone Number

This field is hidden when viewing the form

utm_campaign

This field is hidden when viewing the form

utm_source

This field is hidden when viewing the form

utm_medium

This field is hidden when viewing the form

utm_content

This field is hidden when viewing the form

utm_term

This field is hidden when viewing the form

formid

Phone

This field is for validation purposes and should be left unchanged.

Webinar On Demand

Label-free characterization of challenging transmembrane proteins using Alto digital SPR

Trusted by over 500 research labs worldwide.

Products

Applications

Resources

About

© 2024 Nicoya Lifesciences Inc. All rights reserved. For Research Use Only. Not for use in diagnostic procedures.