Nucleic Acid / Aptamer Interactions
Quantitatively characterize your interaction with binding kinetics & affinity data.
Protein-Aptamer
Ligand: Aptamer (biotinylated) immobilized onto Streptavidin Sensor
Analyte: Lysozyme
kon = 1.8×105 M-1s-1
koff = 2.6×10-3 s-1
KD = 14.6 nM
Outcomes:
- Determine kon and koff (kinetics) and KD (affinity) values
- Quantify levels of protein at different development stages
- Yes/No binding and screening of SELEX aptamers
- Screening for ligand binding partners
- Specificity
Use Cases:
- Aptamer characterization
- Analyzing DNA and RNA interactions
- Expressed protein interactions
- Extracted protein interactions
- Aptamer quality control
- Drug discovery
- Therapeutic and diagnostic applications
- Aptamer biosensor development
See OpenSPR in Action
Discuss your workflows with an application scientist & see how benchtop SPR can help.
Overview
OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.
Make your next scientific breakthrough with OpenSPR.
Discuss your research applications with an SPR application scientist: