Blog

Discovery of a Gene Regulation Network in P. aeruginosa Biofilm Production using OpenSPR Binding Data

Dr. Tung T. Hoang recently published a paper using binding data generated from OpenSPR to quantify the formation of a stable complex between 2 co-regulators of biofilm production and their target DNA binding sequence. Read the full article to see how OpenSPR provided Dr. Hoang with the key binding data needed to authenticate a gene regulation network in P. aeruginosa biofilm production.

The OpenSPR Centre of Excellence – Building a Community of Innovative Researchers in India & Beyond

Dr. Ramaswamy (Dr. Rams) is a leading scientist in India with over 100 publications to date. In collaboration with Dr. Rams and his lab, Nicoya hosted the grand opening of the “OpenSPR Centre of Excellence” at the Institute for Stem Cell Biology and Regenerative Medicine in Bangalore, India.

OpenSPR Binding Data Advances Peptide Screening Methods

Dr. Leonard Luyt recently published a paper using binding data generated from the OpenSPR to quantify the binding behaviour of a chemically synthesized 7 kDa RHAMM “mini-protein” engineered for screening of candidate therapeutic peptides. Read the full article to see how OpenSPR provided Dr. Luyt with the key binding data needed for his latest advancement on therapeutic peptide screening methods.

OpenSPR Binding Data Advances Targeting Potential of Anti-Cancer Therapeutics

Dr. Huile Gao recently published a paper that unveils how protein corona formation may significantly reduce the interaction potential of ligand-modified PNs to target TfR, a common target for anti-cancer therapeutics. Read the full article to see how OpenSPR binding data provided Dr. Huile Gao insight into enhancing drug delivery methods for anti-cancer therapeutics.

OpenSPR Antibody Binding Data Challenges Traditional Hepatitis B Vaccination Strategies

Dr. Yu-Ching Lee recently published a paper challenging traditional hepatitis B vaccination (HBV) strategies through his study of antibody-antigen interactions.

OpenSPR Phospholipid Binding Data Advances Cardiac Health Research

Dr. Zeczycki, a researcher at East Carolina University, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-lipid interaction. Results show that elevated levels of DHA may contribute to various metabolic disease via a reduction in cardiac mitochondrial enzyme activity.

OpenSPR Binding Data Helps Advance Cervical Cancer Therapies

Dr. Zhang recently published a paper demonstrating the disruption potential of small molecules synthesized from taspine-derivatives to combat the Janus kinase/signal transducers and activators of transcription (JAK/Stat) signaling pathway, a known pathway in the development of cervical cancer. Read the full article to see how OpenSPR provided Dr. Zhang with the data needed to publish her protein-small molecule research.

Determination of Protein Concentrations using OpenSPR

Looking for quick, easy and affordable protein concentration analysis? Benchtop SPR can help. In our application note, we demonstrate how OpenSPR™ can be used as a concentration assay for determining the level of α-lactalbumin, an important protein in milk.

OpenSPR Binding Data Helps Advance Biotherapeutic Drug Discovery

Dr. Brown, a researcher at Lehigh University, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-peptide interaction, demonstrating the possibility of using target-based peptides to inhibit leukotoxin mediated cytotoxicity in human white blood cells.

OpenSPR Binding Data Helps Advance Ageing & Cancer Research

Dr. Roth, a researcher at the Medical University of South Carolina, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-protein interaction, helping them discover a direct link between telomere damage–dependent senescence and apoptosis with regards to aging and cancer.

OpenSPR Binding Data Helps Advance Cancer Drug Discovery

Dr. Lu, a researcher at Sichuan University, uses OpenSPR’s surface plasmon resonance technology to get the key binding data needed for their recent publication on protein-protein interaction, helping them discover a new strategy for tumor-targeted delivery of anticancer agents.

How OpenSPR helped Dr. Espie Publish his Groundbreaking Research

Hot New App Note: Temperature Dependent Binding Kinetics of Protein-Protein Interactions Using OpenSPR™