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Application Note

Poster: Multi-Modal Biophysical Characterization of an Antibody-Drug Conjugate: Linking Conformational Properties to Function

Overview Antibody-drug conjugates (ADCs) combine the target specificity of monoclonal antibodies with the cytotoxic potency of small-molecule payloads. A key challenge encountered in the development…

An Integrated icIEF-SPR Workflow for Functional Characterization of Monoclonal Antibody Charge Variants

Biomolecular charge variant characterization has been a challenge that involves a cumbersome and time-consuming process. This study presents a novel and efficient method for determining…

Analysis of Antibody-Antigen Binding Kinetics on Digital SPR using the Protein G Capture Kit

Nicoya’s Protein G Capture Kit allows users to capture antibodies or Fc-tagged proteins directionally, offering an optimal orientation for analyte binding. This method also enables…

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