Presenter:
Rina Dukor
President and Co-Founder
BioTools INC
Overview
Rina, President and Co-Founder at BioTools INC, explores how spectroscopy techniques like circular dichroism (CD), Fourier-transform infrared (FTIR), and Raman spectroscopy play a crucial role in characterising monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs), and adeno-associated viruses (AAVs). She discusses how these tools enhance secondary structure determination and improve biopharmaceutical analysis.
Key Insights from Dr Rina’s Talk:
- CD spectroscopy enables structural characterisation at low concentrations, providing valuable insights into biomolecules.
- A novel algorithm facilitates secondary structure analysis without needing extinction coefficients.
- Traditional mAb characterisation often lacks secondary structure quantification—spectroscopy offers a reliable solution.
- Spectroscopy techniques differentiate full and empty AAV capsids, correlating with potency and efficacy.
- Collaborative efforts are driving the validation and adoption of spectroscopy in biopharma applications.
Discover how Dr Rina’s research is advancing structural analysis in the biopharmaceutical industry!
