Overview
Alto™ is the worldʼs only Digital SPR™ instrument that uses digital microfluidics (DMF) to handle samples. This allows all SPR sensors, samples, buffers and reagents needed for an experiment to be contained in a disposable, automation-compatible cartridge, making Alto the only fully automatable SPR instrument.
Here, we show how Alto seamlessly integrates with the Opentrons Flex™ and Brooks Automation PF400 robot arm to rapidly screen through hybridomas in supernatant with only a few minutes of user intervention.
Nicoyaʼs analysis software automatically analyzes the data from each interaction to identify and provide single concentration kinetics on hits.
