Solutions
This portfolio brings together Nicoya’s digital biosensing technologies and Applied Photophysics’ structural and kinetic characterization to give scientists a more complete view of molecular behavior. By combining complementary biophysical techniques, teams can answer complex questions with greater confidence, gaining clearer insight without adding complexity or sacrificing the rigor they rely on.
Make every experiment move your science forward.
Nicoya’s solutions are designed around real scientific workflows, delivering reliable, reproducible biophysical insight across discovery, characterization, and quality, without unnecessary complexity.Whether you’re screening early candidates, dissecting mechanism of action, or ensuring stability and developability, our integrated portfolio gives you clarity where it matters most.
Products & Instruments
A flexible portfolio designed to support every solution.
SUPR-DSF
Plate-based intrinsic DSF thermal shift screening for rapid binder identification, ranking, and stability assessment.
Ideal for early discovery and developability workflows where speed, scalability, and clear stabilization trends matter.
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Revo
Accessible digital SPR for fast, confident binding kinetics.
Four- or eight-channel digital SPR with automated cartridge workflows and ultra-low sample consumption. Built for modern discovery teams.
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Alto
High-throughput digital SPR for confident hit identification and kinetic ranking at scale.
Designed for teams that need reproducible kinetics across many interactions, users, and experiments.
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OpenSPR
Benchtop SPR for first-pass interaction validation and structure–function exploration.
An approachable entry point for label-free binding studies without sacrificing data quality.
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“We’re confident that the Alto is replicating data we established almost 30 years ago. It’s remarkable to see the same binding characteristics now, using a modern platform.”
Dr. Chris Heger,
Professor, Pharmacology & Neuroscience
University of North Texas, Health Science Center
“The OpenSPR data was critical for getting our research published because it allowed us to experimentally quantify protein-protein interaction, which would otherwise not be possible with pull-down assays. OpenSPR provided us with a cost-effective method to obtain large amounts of accurate data using small amounts of sample!”
Maryam Moazami-Goudarzi,
University of Toronto Mississauga
“The Chirascan system at the Manchester Institute of Biotechnology is used to advance biological, biochemical, and medical research. Our scientists use CD to gain an understanding of how mutations, buffer or stress conditions affect protein structure and to confirm the stereostructure of small molecules. The system is routinely used by more than 25 scientists and is typically in use 90% of the time. The system is intuitive making user training straightforward. Users return to the Chirascan because it is highly reproducible, has excellent signal:noise and delivers results quickly.”
Dr. Derren Heyes,
University of Manchester
“After one training session, I ran my experiments immediately using the LIP chips and looked at protein binding to different lipid mixtures. The data is beautiful and the instrument is by far one of the easiest and user-friendly that I have ever used!”
Dr. Tonya N. Zeczycki,
Assistant Professor of Biochemistry & Molecular Biology
East Carolina University
Find the right solution to your research needs.
