Overview
As the regulatory role of G-quadruplex structures in crucial biological processes emerges, CD spectroscopy can be expected to gain increased importance in their characterization as drug targets for anti-viral and anticancer therapies.
In this study, CD spectroscopy was used as an orthogonal technique to optimize experimental conditions for Mass Spectrometry experiments, which can be used for high-throughput screening in drug development with regards to structural analysis and binding interactions.
