Analyze protein - small molecule binding kinetics with your personal surface plasmon resonance solution. Compact, user-friendly and affordable, Nicoya’s OpenSPR allows for label-free analysis on your own bench. Determine rate and affinity constants (kon, koff, KD), inhibition curves, and protein-small molecule complexes. Interested in working with us on small molecules? Contact us to inquire about our collaborative opportunities.


  • Determine kinetics (kon, koff) and affinity (KD) values
  • Yes/No Binding
  • Determine inhibition
  • Specificity
  • Ranking and screening

Application Highlight

Small-molecule-protein interaction of Ceftazidime to determine kinetics

small molecule binding kinetics

Use Cases

  • Drug discovery
  • Small molecule development
  • Expressed protein interactions
  • Isolated/extracted protein interactions
  • Screening for ligand binding partners