Protein Interaction

Label-free binding and affinity data on your benchtop
OpenSPR is a user-friendly and low maintenance SPR solution that allows researchers to characterize biomolecular interactions in real-time measurements. Analyze the kon, koff, and KD of your protein interaction with Nicoya's OpenSPR. 


  • Determine kon and koff (kinetics) and KD (affinity) values
  • Quantify levels of protein at different development stages and expression levels
  • Yes/No binding
  • Determine presence of protein and antibody
  • Determine levels of crude antibody titer
  • Screening for ligand binding partners
  • Specificity

Application Highlight

Kinetic analysis of a protein-protein interaction using OpenSPR:

Use Cases

  • Expressed protein interactions
  • Extracted protein interactions
  • Crude lysate binding detection and relative quantification
  • Antibodies
  • Quality control
  • Drug discovery
"The OpenSPR is a very versatile and affordable system that has allowed us to accurately measure protein-protein and protein-peptide interactions without the need to label the interacting molecules. It is user-friendly, versatile and the sensor chips are not very expensive. Both graduate and undergraduate students have used the instrument to generate reliable data." Dr. Guy Guillemette

Chemistry, University of Waterloo

Book a Web Demo

Discuss your research applications with an application scientist and learn how OpenSPR works step-by-step.