Antibody Binding Kinetics

Label-Free Antibody Analysis


Analyze protein-antibody interactions with your personal surface plasmon resonance instrument. Compact, user-friendly and affordable, Nicoya’s OpenSPR allows for label-free analysis on your own bench. Determine antibody binding kinetics (kon, koff, and KD) in no time. Tired of time-consuming Western Blots and ELISAs? Determine the concentration of antibody or protein in a sample quicker and without purifying!


  • Determine kon and koff (kinetics) and KD values (Affinity)
  • Quantify levels of protein at different development stages
  • Quantity levels of protein at different expression levels
  • Yes/No binding
  • Determine presence of protein and antibody
  • Determine levels of crude antibody titer
  • Screening for ligand binding partners
  • Specificity

Application Highlight

Protein-antibody interaction analyzed using OpenSPR to determine kinetics

Use Cases

  • Expressed protein interactions
  • Extracted protein interactions
  • Crude lysate binding detection and relative quantification
  • Antibodies
  • Quality control
  • Drug discovery

Book 1-on-1 Web Demo

Book a free live web demo with one of our application scientists to discuss your research applications and learn how OpenSPR works step-by-step.