Nicoya’s Alto digital SPR miniaturizes and automates complex binding assays to simplify vaccine discovery and characterization.
Viruses evolve. So should your research arsenal.
Discover the power of Alto digital SPR today.
Boost your vaccine research with next-gen, label-free digital SPR.
Boost your vaccine research with next-gen, label-free digital SPR.
Ready to get started with Alto? Download the brochure to learn more.
Meet Alto, the best tool for your vaccine research
Where Alto fits in early vaccine development
See it in action
Alto is a small footprint device that eliminates buffer bottles, tubing and daily maintenance routines with a simple integrated cartridge that holds all reagents and automates almost all assay operations.
Alto uses just 2 µL of sample to automatically perform serial dilutions and obtain rich assay data using low amounts of precious samples, without manual dilution pipetting.
Alto digital SPR is the world’s most user-friendly SPR system that simplifies user learning and operation to get great data with minimal effort.
why?
what?
how?
show
me...
Alto digital SPR offers powerful multi-purpose utility with several test methods for many vaccine types and robust tolerance for serum and other complex media.
Alto offers dedicated application modules for binding kinetics, kinetic screening, epitope binning and quantitation for the characterization of vaccine candidates, and of serum antibody response for potency and binding functionality.
Alto can generate data for titer and potency, epitope binning and screening, and accurate binding kinetics for various vaccine types such as live and attenuated strands, toxoid, protein subunit, virus and mRNA vaccines.
why?
what?
how?
show me...
Alto digital SPR generates high-quality, publication-ready data for up to 240 interactions on 48 samples per cartridge in just a few hours in one unattended run, and allows parallel screening of 8 to 16 assay conditions for rapid assay optimization.
why?
what?
Alto accelerates time to results with 16 parallel sensors, 48 sample capacity, 5x automated serial dilutions per sample, screening for 48 samples against 2 antigens per cartridge, robust tolerance of serum, and single/multi-cycle kinetics capabilities.
how?
Alto performs 5 automatic serial dilutions from just
2 µL volume for 48 samples using onboard reagents in the cartridge, and runs up to 16 reactions in parallel.
show me...
Traditional methods used for binding analysis in vaccine discovery and characterization rely on analytical instruments that require significant hands-on experimentation time and labor, large quantities of sample, expensive equipment, and specialized expertise. Modern biopharma and academic institutions' needs make it an imperative to reduce the time and cost in discovery to distribution of vaccines, ensuring quicker responses to health crises and saving lives.
Nicoya's Alto™ digital SPR™ system simplifies titer, screening, epitope binning, binding kinetics, and potency measurements in serum for most vaccines. It features 2 µL sample volumes, 16 parallel sensors, integrated sensor and sample cartridges, and automated assay protocols, all within a compact system. Alto:
Simplifies testing and saves resources.
Adapts to your testing needs to provide unmatched power.
Delivers rapid, high quality results without compromises.
Traditional methods used for binding analysis in vaccine discovery and characterization rely on analytical instruments that require significant hands-on experimentation time and labor, large quantities of sample, expensive equipment, and specialized expertise. Modern biopharma and academic institutions' needs make it an imperative to reduce the time and cost in discovery to distribution of vaccines, ensuring quicker responses to health crises and saving lives.
Nicoya's Alto™ digital SPR™ system simplifies titer, screening, epitope binning, binding kinetics, and potency measurements in serum for most vaccines. It features 2 µL sample volumes, 16 parallel sensors, integrated sensor and sample cartridges, and automated assay protocols, all within a compact system. Alto:
Simplifies testing and saves resources.
Adapts to your testing needs to provide unmatched power.
Delivers rapid, high quality results without compromises.
Alto is a small footprint device that eliminates buffer bottles, tubing and daily maintenance routines with a simple integrated cartridge that holds all reagents and automates almost all assay operations.
Alto uses just 2 µL of sample to automatically perform serial dilutions and obtain rich assay data using low amounts of precious samples, without manual dilution pipetting.
Alto digital SPR is the world’s most user-friendly SPR system that simplifies user learning and operation to get great data with minimal effort.
why?
what?
how?
show
me...
Simplifies testing and saves resources.
Alto digital SPR offers powerful multi-purpose utility with several test methods for many vaccine types and robust tolerance for serum and other complex media.
Alto offers dedicated application modules for binding kinetics, kinetic screening, epitope binning and quantitation for the characterization of vaccine candidates, and of serum antibody response for potency and binding functionality.
Alto can generate data for titer and potency, epitope binning and screening, and accurate binding kinetics for various vaccine types such as live and attenuated strands, toxoid, protein subunit, virus and mRNA vaccines.
why?
what?
how?
show me...
Adapts to your testing needs to provide unmatched power.
Alto digital SPR generates high-quality, publication-ready data for up to 240 interactions on 48 samples per cartridge in just a few hours in one unattended run, and allows parallel screening of 8 to 16 assay conditions for rapid assay optimization.
why?
what?
Alto accelerates time to results with 16 parallel sensors, 48 sample capacity, 5x automated serial dilutions per sample, screening for 48 samples against 2 antigens per cartridge, robust tolerance of serum, and single/multi-cycle kinetics capabilities.
how?
Alto performs 5 automatic serial dilutions from just 2 µL volume for 48 samples using onboard reagents in the cartridge, and runs up to 16 reactions in parallel.
show me...
Delivers rapid, high quality results without compromises.